Segmentation of Pericardial Adipose Tissue in CMR Images: a Benchmark Dataset MRPEAT and a Triple-Stage Network 3SUnet
The increased pericardial adipose tissue (PEAT) is associated with a series of cardiovascular diseases (CVDs) and metabolic syndromes. Therefore, particular emphasis should be placed on PEAT quantification and its role in CVD development and progression. In addition, given the more promising clinical value of quantifying PEAT in cardiovascular magnetic resonance (CMR) images than computed tomography (CT) images in CVD assessment, an accurate and time-saving PEAT measurement based on CMR is indispensable.
However, almost all existing studies are based on computed tomography (CT) diagnostic modality. Although there is a study segmenting EAT in CMR images in the standard four-chamber(4CH) view, this dataset is unavailable and cardiac short axis (SA) MR images are more prevalent in CVD diagnosis. Segmentation of PEAT in cardiac SA MR images still an pending problem due to the following challenges, 1) the absence of public CMR datasets, 2) diversity in shape, size and location of PEAT, 3) severe class imbalance , and 4) heavily overlapping in intensity.
To address the above challenges, we release a benchmark dataset and propose a deep learning model to segment PEAT in cardiac SA MR images. The main contributions of our paper are given as follows.